发明名称 |
Methods for alleviating statin myopathy |
摘要 |
Disclosed herein are methods and compositions for alleviating side effects of statin administration, such as myopathic or myalgic side effects, short-term memory loss, abnormal liver function, glucose intolerance, hyperglycemia, increased risk for diabetes, or cumulative trauma disorder, comprising administration of β-hydroxy β-methylbutyrate (HMB) to an individual taking a statin. Also disclosed are methods and compositions for alleviating acute rhabdomyolysis comprising administration of HMB. The disclosure further provides uses of HMB in combination with a statin to alleviate side effects of statin administration. |
申请公布号 |
US9399026(B2) |
申请公布日期 |
2016.07.26 |
申请号 |
US201514853374 |
申请日期 |
2015.09.14 |
申请人 |
Winterfield Roland W. |
发明人 |
Winterfield Roland W. |
分类号 |
A61K31/19;A01N37/00;A61K31/21;A61K31/366;A61K31/40;A61K31/4418;A61K31/505;A61K31/22;A61K31/405;A61K31/47 |
主分类号 |
A61K31/19 |
代理机构 |
McDonnell Boehnen Hulbert & Berghoff LLP. |
代理人 |
McDonnell Boehnen Hulbert & Berghoff LLP. |
主权项 |
1. A method for alleviating one or more side effects of statin administration, the method comprising supplementing statin administration with administration of a therapeutically effective amount of β-hydroxy β-methylbutyrate (HMB). |
地址 |
Hinsdale IL US |