发明名称 |
Bioerodible polymers useful for the controlled release of therapeutic agents |
摘要 |
Bioerodible ortho ester polymers useful for preparing soft form bioerodible pharmaceutical compositions such as ointments, creams, gels and the like are provided. A novel synthetic method for preparing the polymers is provided as well. Synthesis involves a one-step reaction between a monomeric ortho ester and a triol. The pharmaceutical compositions of the invention are useful for the controlled release of therapeutic agents, and may be administered for a variety of purposes, such as for the treatment of deep wounds, including burns, and for the treatment of periodontal disease.
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申请公布号 |
US5030457(A) |
申请公布日期 |
1991.07.09 |
申请号 |
US19890400532 |
申请日期 |
1989.08.28 |
申请人 |
PHARMACEUTICAL DELIVERY SYSTEMS, INC. |
发明人 |
NG, STEVE Y. W.;HELLER, JORGE |
分类号 |
A61K9/20;A61K47/34;C08G65/34 |
主分类号 |
A61K9/20 |
代理机构 |
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地址 |
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