| 摘要 |
The present invention provides adipose tissue modified with a vector comprising or encoding, in which case it expresses, an anti-angiogenic factor, an angiogenic substance, an apoptotic factor, an adipsin protein or an Ob protein. Also provided is adipose tissue modified with a vector comprising a promoter and, operably linked thereto, a DNA sequence encoding a secreted protein. Methods of therapeutically treating adipose tissue and expressing a secreted protein in adipose tissue are also provided. The adipose tissue is optionally in the form of an implant, which can further comprise a lymphogenic protein or a vector that comprises and expresses a lymphogenic gene. |
