Fast DNA sequence determination method by measuring energy of base pairing or unpairing of nucleic acid sequences and use thereof in sequencing and diagnostics

摘要

PCT No. PCT/FR94/00382 Sec. 371 Date Feb. 12, 1996 Sec. 102(e) Date Feb. 12, 1996 PCT Filed Apr. 6, 1994 PCT Pub. No. WO94/23065 PCT Pub. Date Oct. 13, 1994A method for determining a DNA or RNA sequence, comprising determining the paring or separating energy between each base pair of the DNA or a double-stranded RNA/DNA hybrid corresponding to the DNA or RNA sequence to be determined, and comparing said energy with predetermined values.