发明名称 |
TRICYCLIC BENZIMIDAZOLES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS |
摘要 |
The invention provides for a compound of formula (I) or a pharmaceutically acceptable salt thereof; wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, A, B, D, m, n, x, andy are defined as described in the specification. The invention additionally provides a pharmaceutically composition comprising the compound of formula (I), together with a method of using the same to treat or prevent neurological and psychiatric disorders. The compounds are useful in therapy related to the treatment or prevention of mGluR2 receptor-mediated disorders. |
申请公布号 |
WO2007018998(A3) |
申请公布日期 |
2007.05.03 |
申请号 |
WO2006US28165 |
申请日期 |
2006.07.21 |
申请人 |
ASTRAZENECA AB;NPS PHARMACEUTICALS, INC.;ISAAC, METHVIN;SLASSI, MALIK;EGLE, IAN;MA, FUPENG |
发明人 |
ISAAC, METHVIN;SLASSI, MALIK;EGLE, IAN;MA, FUPENG |
分类号 |
C07D471/06;A61K31/437;A61P25/00;C07D487/06;C07D498/06 |
主分类号 |
C07D471/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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