发明名称 BENZOTHIOPHENE DERIVATIVES USEFUL IN THERAPY
摘要 Compounds of formula I, <IMG> wherein X represents O or S(O)m; R1 and R2 independently represent phenyl, naphthyl or heteroaryl; each of which is optionally fused and optionally substituted; Y represents a bond, O, (CH2)n, O(CH2)n, (CH2)n O, or CH(C1-6 alkyl)O; R3 represents H or C1-6 alkyl; m represents 0, 1, or 2; and n represents 1, or 2; and pharmaceutically acceptable salts thereof, are useful in therapy, in particu lar in the treatment of restenosis, renal failure and pulmonary hypertension.
申请公布号 CA2255165(A1) 申请公布日期 1999.06.08
申请号 CA19982255165 申请日期 1998.12.04
申请人 PFIZER INC. 发明人 DICKINSON, ROGER PETER;DACK, KEVIN NEIL
分类号 A61K31/00;A61K31/38;A61K31/381;A61K31/41;A61K31/415;A61K31/4164;A61K31/4178;A61K31/4196;A61K31/425;A61K31/427;A61K31/435;A61K31/4353;A61K31/437;A61K31/44;A61K31/4427;A61K31/4433;A61K31/4436;A61K31/495;A61K31/4965;A61K31/497;A61K31/50;A61K31/501;A61K31/505;A61K31/506;A61P9/00;A61P9/10;A61P11/00;A61P13/00;A61P13/08;A61P13/12;A61P15/00;A61P15/10;C07D333/70;C07D409/06;C07D409/12;C07D409/14;C07D417/12;C07D471/04;C07D521/00;(IPC1-7):C07D333/70 主分类号 A61K31/00
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