| 摘要 |
The subject of the present invention is the use of bisphosphonic acid derivatives of formula (I): <IMAGE> in which: - R1 represents a hydrogen atom, a halogen atom, a hydroxyl, an amino, a monoalkyl(C1-C4)amino, a dialkyl(C1-C4)amino; - R2 represents a halogen atom, a linear alkyl containing from 1 to 5 carbon atoms which is unsubstituted or substituted with a group chosen from a chlorine atom, a hydroxyl, an amino, a monoalkyl(C1-C4)amino, a dialkyl(C1-C4)amino, a cycloalkyl(C3-C7)amino, or R2 represents a phenoxy, a phenyl, a thiol, a phenylthio, a chlorophenylthio, a pyridyl, a pyridylmethyl, a 1-pyridyl-1-hydroxymethyl, an imidazolylmethyl or a thiomorpholin-4-yl; and the use of the salts thereof with pharmaceutically acceptable inorganic or organic acids, for the preparation of medicaments for promoting bone repair, in human or veterinary medicine. |
