发明名称 METHOD OF TREATING PROLIFERATIVE DISORDERS AND OTHER PATHOLOGICAL CONDITIONS MEDIATED BY BCR-ABL, C-KIT, DDR1, DDR2 OR PDGF-R KINASE ACTIVITY BCR-ABLC-KITDDR1DDR2 PDGF-R
摘要 The present invention relates to a regimen for the administration of a pyrimidylaminobenzamide of formula I wherein the radicals as defined herein, or of a pharmaceutically acceptable salt thereof, for the treatment of proliferative disorders, particularly solid and liquid tumors, and other pathological conditions mediated by the Bcr-Abl oncoprotein, the cell transmembrane tyrosine kinase receptor c-Kit, DDR1 (discoidin domain receptor 1), DDR2 (discoidin domain receptor 2) or PDGF-R (platelet derived growth factor receptor) kinase activity, wherein the pyrimidylaminobenzamide of formula I and, optionally, pharmaceutically acceptable carriers, are dispersed in a fruit preparation.
申请公布号 HK1169950(A1) 申请公布日期 2016.08.12
申请号 HK20120110734 申请日期 2012.10.26
申请人 Novartis AG 发明人 GALLAGHER, Neil;YIN, Ophelia
分类号 A61K;A61P;C07D 主分类号 A61K
代理机构 代理人
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