发明名称 Reduction of skin irritation during electrotransport delivery
摘要 The invention is directed to a composition and product for use in an electrotransport device. The composition includes an ionized drug, an anti-inflammatory agent and a solvent. Preferably, the anti-inflammatory agent is hydrocortisone or esters thereof, and the solvent is an alcohol, a glycol, a glycerol, a cyclodextrin, a nonionic surfactant or mixtures thereof. The composition preferably further includes a gel matrix that is a swellable, hydrophilic polymer, a water soluble hydrophilic polymer or a solid polymer. A hydrophobic polymer and/or additives may also be included.
申请公布号 US5865792(A) 申请公布日期 1999.02.02
申请号 US19970895096 申请日期 1997.07.16
申请人 ALZA CORPORATION 发明人 LEDGER, PHILIP W.;CORMIER, MICHEL J.N.;CAMPBELL, PATRICIA S.
分类号 A61N1/30;A61N1/32;(IPC1-7):A61N1/30 主分类号 A61N1/30
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