摘要 |
NEW MATERIAL:A compound shown by formula I (R<1> and R<2> are H, halogen or polyfluorocarbon; R<3>-R<6> are H, alkyl, aralkyl or aryl; R<7> and R<8> are H, alkyl, aralkyl, etc.). EXAMPLE:N,N-Diethyl-2-oxo-4-perfluorooctylbutanamide. USE:An intermediate for synthesizing fluoroheterocyclic compound or fluorine- containing amino acid capable of becoming a herbicide or an antitumor agent. PREPARATION:An iodine-containing alkyl iodide shown by formula II is reacted with an amino acid shown by formula III and carbon monoxide in the presence of a palladium catalyst at 20-150 deg.C to give a compound shown by formula I. |