发明名称 |
Process of preparing 2,2'-(1-Methyl-1,2-Ethanediylidene) bis (Hydrazine carboximidamide) |
摘要 |
<p>The invention concerns a process for preparing 2,2'-(1-methyl-1,2-ethanediylidene)bisÄhydrazine carboximidamideÜ comprising the steps of : a) reacting aminoguanidine hydrochloride with methylglyoxal aldehyde or methylglyoxal dimethyl acetal in an acidic aqueous reaction medium to produce 2,2'-(1-methyl-1,2-ethanediylidene)bisÄhydrazine carboximidamideÜ; and b) purifying the 2,2'-(1-methyl-1,2-ethanediylidene)bisÄhydrazine carboximidamideÜ by recrystallization from an acidic aqueous medium.</p> |
申请公布号 |
EP0782983(A2) |
申请公布日期 |
1997.07.09 |
申请号 |
EP19970400361 |
申请日期 |
1997.02.18 |
申请人 |
SANOFI |
发明人 |
PHILION, RICHARD;ELENBAAS, STEVEN A. |
分类号 |
A61K31/00;A61K31/155;A61P35/00;C07C281/10;C07C281/18;(IPC1-7):C07C277/08 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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