The present invention relates to compositions and methods for treating inflammation and other pathological conditions using novel blocking P-selectin antibodies that inhibit adhesion of leukocytes to activated platelets and/or to activated vascular endothelium in vivo. Both murine and humanized antibodies are provided.
申请公布号
FI955261(A)
申请公布日期
1996.01.03
申请号
FI19950005261
申请日期
1995.11.02
申请人
CYTEL CORPORATION
发明人
CHESNUT, ROBERT W.;POLLEY, MARGARET J.;PAULSON, JAMES C.;JONES, S. TARRAN;SALDANHA, JOSE W.;BENDIG, MARY M.;KRIEGLER, MICHAEL;PEREZ, CARL;BAYER, ROBERT;NUNN, MICHAEL