Compounds and methods for treating influenza

摘要

This invention is directed to methods for treating and preventing influenza infection by inhibiting influenza virus HA maturation processes employing compounds of formula I. It is also directed to combinations for treating and preventing influenza infection comprising compounds of formula I and other agents.

主权项

1. A method of treating viral infection caused by an influenza virus comprising administering to a patient in need thereof a therapeutically effective amount of a compound of formula I wherein at least one of R1, R2, R3 is OH or an ester thereof; R4, R5, and the remainder of R1, R2, and R3, are H; and R6 is NO2 and R9 is H, or a pharmaceutically acceptable salt thereof.