发明名称 METHOD FOR TREATING TUMORS HAVING HIGH LDL REQUIREMENTS EMPLOYING MTP INHIBITORS
摘要 A method is provided for treating hematologic tumors and solid tumors, including certain types of leukemias and metastatic tumors, having high LDL requirements employing a delipidating agent such as an MTP inhibitor to substantially reduce LDL blood levels. In addition, a method is provided for treating tumors of the above types having high LDL requirements, especially hematologic tumors such as certain leukemias, employing a delipidating compound to substantially remove native LDL, and then administering a cytotoxic agent carried in reconstituted LDL.
申请公布号 CA2261162(A1) 申请公布日期 1998.01.29
申请号 CA19972261162 申请日期 1997.07.14
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 FIRESTONE, RAYMOND A.
分类号 A61K45/00;A61K31/00;A61K31/4468;A61K31/453;A61K31/4535;A61K31/454;A61K45/06;A61P35/00;A61P35/02;A61P35/04;A61P43/00;(IPC1-7):A61K31/445;A61K31/495;A61K31/505;A61K31/535 主分类号 A61K45/00
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