| 发明名称 |
pH-titratable polyampholytes for delivering polyions to a cell |
| 摘要 |
A polyampholyte is utilized in a condensed polynucleotide complex for purposes of nucleic acid delivery to a cell. The complex can be formed with an appropriate amount of positive and/or negative charge such that the resulting complex can be delivered to the extravascular space and may be further delivered to a cell.
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| 申请公布号 |
US7033607(B2) |
申请公布日期 |
2006.04.25 |
| 申请号 |
US20020095789 |
申请日期 |
2002.03.11 |
| 申请人 |
MIRUS BIO CORPORATION |
发明人 |
TRUBETSKOY VLADIMIR S.;HAGSTROM JAMES E.;BUDKER VLADIMIR G.;WOLFF JON A.;ROZEMA DAVID B.;MONAHAN SEAN D. |
| 分类号 |
A61K9/127;A61K31/713;A61K47/48;C12N15/88 |
主分类号 |
A61K9/127 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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