| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide injectable polysaccharide-cell compositions to be used for a method of correcting defects, more specifically, vesicoureteral reflux, incontinence, or others. <P>SOLUTION: Slowly polymerizing polysaccharide hydrogels have been demonstrated to be useful as a means of delivering a large number of isolated cells via injection. The gels promote engraftment and provide three-dimensional templates for new cell growth. The resulting tissue is similar in composition and histology to naturally occurring tissue. This method can be used for a variety of reconstructive procedures, including custom molding of cell implants to reconstruct three-dimensional tissue defects as well as general implantation of tissues. Their practical examples indicate the building of muscles and cartilaginous tissue, which is useful for correcting defects such as reflux and incontinence. <P>COPYRIGHT: (C)2008,JPO&INPIT |
