| 发明名称 | Controlled release particles | ||
| 摘要 | A controlled release particle includes a core formed by suspension polymerization of a core ingredient component containing an antibiotic compound and a first polymerizable vinyl monomer, and containing a first polymer of the first polymerizable vinyl monomer and the antibiotic compound present in the first polymer; and a shell formed by suspension polymerization of a second polymerizable vinyl monomer having affinity with water of the same or higher than that of the first polymerizable vinyl monomer, containing a second polymer obtained from the second polymerizable vinyl monomer, and covering the core. | ||
| 申请公布号 | US9511030(B2) | 申请公布日期 | 2016.12.06 |
| 申请号 | US201214003271 | 申请日期 | 2012.03.08 |
| 申请人 | OSAKA GAS CHEMICALS CO., LTD. | 发明人 | Oshima Junji;Sugiyama Takayuki |
| 分类号 | A61K9/50;A01N25/28 | 主分类号 | A61K9/50 |
| 代理机构 | Buchanan, Ingersoll & Rooney PC | 代理人 | Buchanan, Ingersoll & Rooney PC |
| 主权项 | 1. A controlled release particle consisting of: a core formed by suspension polymerization of a core ingredient component containing an antibiotic compound and a first polymerizable vinyl monomer, the core ingredient component being prepared in the absence of a solvent and thus the core ingredient component is solvent-free andcontaining a first polymer of the first polymerizable vinyl monomer, and the antibiotic compound present in the first polymer; and a shell formed by suspension polymerization of a second polymerizable vinyl monomer having affinity with water of the same or higher than that of the first polymerizable vinyl monomer,containing a second polymer obtained from the second polymerizable vinyl monomer, andcovering the core, wherein the antibiotic compound is dispersed in a matrix composed of the first polymer in the core. | ||
| 地址 | Osaka-Shi JP | ||