发明名称 Di-amino-substituted heterocyclic compounds and methods of use
摘要 The present invention comprises a new class of compounds capable of modulating the c-kit receptor and, accordingly, useful for treatment of c-kit mediated diseases, including various fibrotic and mast cell related diseases such as mastocytosis. The compounds have a general Formula I wherein R1-6, X and Y are defined herein. The invention further comprises pharmaceutical compositions, methods for treatment of c-kit mediated diseases, and intermediates and processes useful for the preparation of compounds of the invention.
申请公布号 US2008318946(A1) 申请公布日期 2008.12.25
申请号 US20070879832 申请日期 2007.07.18
申请人 AMGEN INC. 发明人 CHEN NING;HU ESSA
分类号 A61K31/506;A61K31/5377;A61P35/00;A61P37/02;C07D413/14 主分类号 A61K31/506
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