发明名称 |
SYNTHETIC DIVALENT sLex CONTAINING POLYLACTOSAMINES AND METHODS FOR USE |
摘要 |
The present invention is directed to novel compositions and their use in the treatment of inflammatory responses. Specifically, the invention is directed to novel synthetic oligosaccharide constructs and their use to block lymphocyte binding to correspondent oligosaccharides on the endothelial surface, and thus reduce or otherwise ameliorate an undesired inflammatory response. The invention is further directed to the use of such constructs in other disease states characterized by selectin binding, such as bacterial infections and metastatic cancers. |
申请公布号 |
WO9912944(A3) |
申请公布日期 |
1999.08.26 |
申请号 |
WO1998FI00688 |
申请日期 |
1998.09.04 |
申请人 |
GLYCIM OY |
发明人 |
RENKONEN, OSSI;RENKONEN, RISTO |
分类号 |
C07H15/12;A61K31/70;A61K31/702;A61K31/7028;A61K31/715;A61K31/726;A61P1/04;A61P11/00;A61P17/00;A61P19/02;A61P29/00;A61P31/00;A61P31/04;A61P35/04;A61P37/06;C07H;C07H1/00;C07H7/02;C07H13/04;C07H17/04;C08B37/00;C12P19/04;C12P19/18;C12P19/26 |
主分类号 |
C07H15/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|