NON-INVASIVE VACCINATION THROUGH THE SKIN

摘要

The present invention relates to novel vaccines for the non-invasive, transcutaneous administration of antigens associated with ultradeformable carriers, for the purpose of prophylactic or therapeutic vaccination. The vaccines comprise (a) a transdermal carrier which is a penetrant, (b) a compound which specifically releases or specifically induces cytokine or ant i- cytokine acitvity or exerts such an activity itself, and (c) an antigen, an allergen, a mixture of antigens an/or mixture of allergens. The invention further relates to methods for the vaccination of mammals for obtaining a protective or therapeutic immune response.