| 发明名称 |
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE |
| 摘要 |
<p>The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherpeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.</p> |
| 申请公布号 |
CA2312361(A1) |
申请公布日期 |
1999.06.10 |
| 申请号 |
CA19982312361 |
申请日期 |
1998.11.30 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
DESOLMS, S. JANE |
| 分类号 |
C07D401/12;E21B47/01;(IPC1-7):A61K31/55;C07D403/12;C07D401/14;C07D403/14;A61K31/445 |
主分类号 |
C07D401/12 |
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