| 发明名称 | Lactic acid bacteria and its applications in immunomodulation and anti-inflammation | ||
| 摘要 | The invention provides a new lactic acid bacteria (LAB) strain with immunomodulatory and anti-inflammatory activity and a composition containing and method using the same. The LAB of the invention can be administrated for modulating an immune response in order to restore or prevent metabolic disorders caused by obesity or chronic inflammation. | ||
| 申请公布号 | US9399048(B2) | 申请公布日期 | 2016.07.26 |
| 申请号 | US201414198020 | 申请日期 | 2014.03.05 |
| 申请人 | ASIAN PROBIOTICS AND PREBIOTICS LTD | 发明人 | Tsai Ying-Chieh;Wu Chien-Chen;Liao Jian-Fu |
| 分类号 | A61K39/02;A61K35/747;A23L1/30;A23L2/52;A61K39/09;C12R1/25 | 主分类号 | A61K39/02 |
| 代理机构 | WPAT, P.C., Intellectual Property Attorneys | 代理人 | WPAT, P.C., Intellectual Property Attorneys ;King Anthony |
| 主权项 | 1. A method of enhancing immunomodulatory and/or anti-inflammatory activity, comprising administering the lactic acid bacteria of the a composition comprising an isolated lactic acid bacteria and an edible carrier to a subject, wherein the isolated lactic acid bacteria is Lactobacillus plantarum subsp, plantarum having 16S rRNA gene and pheS gene containing the nucleic acid sequences as shown in the SEQ ID NO: 1 and SEQ ID NO: 2; wherein the isolated lactic acid bacteria is Lactobacillus plantarum subsp, plantarum K21, deposited with DSMZ-DEUTSCHE SAMMLUNG VON MIKROORGANISMEN UND ZELLKULTUREN (DSMZ) under accession number DSM 27444. | ||
| 地址 | Mahe SC | ||