发明名称 Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof
摘要 The invention relates to salts of (4R-cis) -(1,1-dimethyl -ethyl) -6-(2-aminoethyl) -2,2-dimethyl -1,3-dioxane -4-acetate of formula (I) formed with organic acids. The new salts according to the invention are stable and can be easily purified by recrystallization. The new salts of the invention are valuable pharmaceutical intermediates which can be used e.g. in the preparation of the hypolipidemic agent having the generic (INN) name atorvastatin. The invention further relates to the preparation of the new salts of the compound of formula (I).
申请公布号 AU4600200(A) 申请公布日期 2000.11.21
申请号 AU20000046002 申请日期 2000.05.05
申请人 EGIS GYOGYSZERGYAR RT. 发明人 PETER KOTAY NAGY;ZOLTAN GREFF;JOZSEF BARKOCZY;GYULA SIMIG;LASZLO BALAZS;IMRE DOMAN;ZOLTAN RATKAI;PETER SERES;FERENC BARTHA;GYORGYI VERECZKEYNE DONATH;KALMAN NAGY
分类号 C07D319/06 主分类号 C07D319/06
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