| 摘要 |
PROBLEM TO BE SOLVED: To provide a cyclic aminomethyl pyrimidine derivative and a pharmaceutically acceptable salt thereof exhibiting effects on dopamine Dreceptor with high selectivity and useful as a treatment agent of central nervous system diseases such as attention deficit hyperkinesis disorder.SOLUTION: There is provide a compound represented by the formula (1) and a pharmaceutically acceptable salt thereof. (1), where n and m are each independently 1 or 2, Ris a Calkyl group, a Ccycloalkyl group or an amino group, Ris H, a Calkyl group or an alkyl group-substituted/unsubstituted amino group, Ris H when Ris the amino group, Rand Rare each independently H or a Calkyl group, Rand Rare each independently H, F or a Calkyl group, a ring Q is substituted/unsubstituted 5- to 10-membered nitrogen-containing heteroaryl group and bond containing break lines is a single bond or a double bond.SELECTED DRAWING: None |
