Anti-idiotype antibodies, process for preparing them and method of determining antibody.

摘要

This invention provides an anti-idiotype antibody to a specific antibody recognizing a carbohydrate linkage selected from the group consising of the formula NeuAc alpha 2->3Gal beta 1->4GlcNAc(3-> alpha 1Fuc) beta 1->3Gal beta 1->4GlcNAc(3<- alpha 1Fuc) beta 1->3Gal beta 1->4Glc- , the formula Gal beta 1->4GlcNAc(3<- alpha 1Fuc) beta 1->3Gal beta 1->, the formula Fuc alpha 1->2Gal beta 1->4GlcNAc(3-> alpha 1Fuc) beta 1->3Gal beta 1->, the formula NeuAc alpha 2->3Gal beta 1->3GlcNAc(4-> alpha 1Fuc) beta 1->3Gal beta 1->, the formula NeuAc alpha 2->3Gal beta 1->3GlcNAc(4-> alpha 1Fuc)(6<- alpha 2NeuAc) beta 1->3Gal beta 1-> and the formula NeuAc alpha 2->3Gal beta 1->3GlcNAc(6<- alpha 2NeuAc) beta 1->3Gal beta 1->, a process for preparing the same and a method for determining a cancer antigen used the same.