IN VIVO POLYMERIZABLE OPHTHALMIC COMPOSITIONS

摘要

Ophthalmic compositions containing biocompatible, bioadhesive polymerizable amphipathic mesophase materials useful for repairing retinal tissue tears or retinal detachments are disclosed. In one embodiment, the polymerizable materials, which comprise substituted fluoroalkyl or perfluoroalkyl monomers having anionic, cationic, and/or nonionic surface active functionality in the unsaturated fluorophobic ends, are polymerized in vivo to provide effective, long-lasting repair of torn, ruptured or detached retinal tissue. Ophthalmic applications of these materials are not limited to retinal repair.