主权项 |
1. An arylpyrrolidine compound of Formula (I) wherein R1 is CF3; R2 is hydroxy; n is 1; A is C—X3; X1, X2, X3 and X4 each independently are hydrogen, fluoro, chloro, bromo, iodo or C1-4 haloalkyl; B1 is C—H or C—F; B2 is C—H, C—F, C—Cl, C—Br, C—I, C—CH3, C—CH2CH3, C—CF2H, C—CF3, C—OCF2H or C—OCF3; B3 is C—H; B4 is C—H or C—F; G is a chemical moiety (ε) wherein R3 is hydrogen, C1-4 alkyl, C1-4 haloalkyl, C3-4 alkenyl, C1-6 alkyl-carbonyl, C1-6 alkoxy-carbonyl or C1-12 haloalkoxy-carbonyl; R5 and R6 each independently are hydrogen, cyano, C1-4 alkyl, C1-4 haloalkyl or cyclopropyl; R7 is C1-6 alkyl, C1-6 cyanoalkyl, C1-6 haloalkyl, C3-6 cycloalkyl that is optionally substituted with 1 to 5 fluorine, chlorine, or C1-4 haloalkyl, C3-6 cycloalkyl-C1-4 alkyl that is optionally substituted with 1 to 5 fluorine or chlorine, C3-6 halocycloalkyl-C1-6 alkyl, C2-6 alkenyl, C2-6 haloalkenyl, C1-4 alkoxy, C1-4 haloalkoxy, C1-4 alkoxy-C1-4 alkyl, C1-4 alkoxy-C1-4 haloalkyl, C1-4 alkyl-S—C1-4 alkyl that is optionally substituted with fluorine or chlorine, C1-4 alkyl-S(O)—C1-4 alkyl that is optionally substituted with fluorine or chlorine, C1-4 alkyl-S(O)2-C1-4 alkyl that is optionally substituted with fluorine or chlorine, phenyl, phenyl-C1-6 alkyl, methylamino that is optionally substituted with 1 to 3 fluorine or chlorine, dimethylamino that is optionally substituted with 1 to 5 fluorine or chlorine, ethylamino that is optionally substituted with 1 to 5 fluorine or chlorine, cyclopropylamino that is optionally substituted with 1 to 4 fluorine or chlorine, or prop-2-yn-1-ylamino that is optionally substituted with 1 to 3 fluorine or chlorine; W is oxygen or sulfur; and m is 1. |