发明名称 |
Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation field of the invention |
摘要 |
SUMMARY OF THE INVENTION The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of: a) contacting a pro-chiral sulphide of formula (II) with a metal chiral complex, a base and an oxidizing agent in an organic solvent; and optionally b) isolating the obtained sulphoxide of formula (I).
wherein Ar, Y, R 1 are as defined in claim 1. |
申请公布号 |
ZA200707267(B) |
申请公布日期 |
2008.09.25 |
申请号 |
ZA20070007267 |
申请日期 |
2007.08.28 |
申请人 |
CEPHALON FRANCE |
发明人 |
PRAT, LAURENCE;NECKEBROCK, OLIVIER;SCHWEIZER, DOMINIQUE;LOUVET, PHILLIPPE |
分类号 |
C07C;C07D |
主分类号 |
C07C |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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