发明名称 BACTERIAL GHOSTS AS CARRIER AND TARGETING VEHICLES
摘要 The invention concerns the use of bacterial ghosts as carrier and targeting vehicles for active substances.
申请公布号 US2016220499(A1) 申请公布日期 2016.08.04
申请号 US201615091825 申请日期 2016.04.06
申请人 Lubitz Werner 发明人 Lubitz Werner;Huter Veronika
分类号 A61K9/50;A61K38/46 主分类号 A61K9/50
代理机构 代理人
主权项 1. A method for preparation of a bacterial ghost containing an active substance encapsulated therein, comprising: (i) preparing a bacterial ghost comprising a receptor, wherein the receptor is a heterologously expressed polypeptide integrated into a cytoplasmic membrane of the bacterial ghost comprising the receptor, and (ii) encapsulating the active substance in the bacterial ghost comprising the receptor prepared in step (i), wherein the active substance is present in the bacterial ghost in the immobilized form by interactions with the receptor.
地址 Kritzendorf AT