Use of an immunodeficiency-virus suppressing lymphokine (ISL) to inhibit the replication of viruses, in particular of retroviruses

摘要

An isolated polypeptide which inhibits the replication of retroviruses in peripheral blood lymphocytes and i) is coded by the DNA sequence shown in SEQ ID NO:1 or complementary sequences, ii) is coded by DNA sequences which hybridize with SEQ ID NO:1 or SEQ ID NO:3 under stringent conditions, iii) is coded by DNA sequences which, if there was no degeneracy of the genetic code would hybridize under stringent conditions with the sequences defined in i) to ii), is useful as a therapeutic agent for the treatment of viral infections and benign and malignant proliferation diseases and as a diagnostic agent for said diseases.