| 摘要 |
PROBLEM TO BE SOLVED: To obtain a new protein useful in screening an agonist/antagonist. SOLUTION: This invention relates to a rat-origin protein or its salt; a DNA encoding the protein; a method for determining a ligand to the protein; a method/a kit for screening a compound changing the binding properties of the ligand to the protein; compounds obtained by the screening or salts thereof; or the like. The rat-origin protein or the DNA encoding the protein can be used in (1) determination of the ligand to the protein, (2) a prophylactic and/or therapeutic agent for diseases related to insufficiency of the protein and (3) screening, or the like, of the compound (agonist, antagonist, or the like) changing the binding properties of the ligand to the protein. |
