发明名称 Cationic complexes of technetium 99m, and ligands therefor.
摘要 A tridentate mono-anionic ligand having the structure R2X - A - YR - Q - Z where X is P, As or N Y is P, As or N Z is phenolic OH, thiophenol or thiol, each of A and Q is a C1-C4 hydrocarbon bridge, two adjacent C atoms of which may form part of a benzene ring and which may carry at least one C1-C4 alkyl, alkoxy alkyl, alkoxy or tetrahydropyran substituent, R may be the same of different at different places in the molecule, and in each case is selected from C1 to C4 alkyl, alkoxy, alkoxyalkyl and alkoxyalkoxy alkyl. The ligands form cationic complexes with Technetium-99m, having imaging properties.
申请公布号 EP0386873(A1) 申请公布日期 1990.09.12
申请号 EP19900300630 申请日期 1990.01.22
申请人 AMERSHAM INTERNATIONAL PLC 发明人 KELLY, JAMES DUNCAN;CHIU, KWOK WAI;GRIFFITHS, DAVID VAUGHAN;DILWORTH, JONATHAN ROBIN
分类号 A61K51/00;A61K51/04;C07F9/50;C07F9/72;C07F9/74;C07F13/00 主分类号 A61K51/00
代理机构 代理人
主权项
地址