Preparation of process of L-methionine

摘要

The present invention relates to a method for producing L-methionine using a bio-synthesis process and a specific enzymatic process. More particularly, the present invention relates to a method for producing L-methionine with high yield by enzyme conversion reaction from L-methionine precursor in the presence of methyl mercaptan (CH3SH). The process of the present invention enables selective production of L-methionine which may be used in various fields of industry, such as feed- and food-additives, as raw material for medical supplies, pharmaceutical drugs, and the like.

主权项

1. A process comprising enzymatic converting of an L-methionine precursor with methyl mercaptan in a reaction vessel to obtain L-methionine, wherein the methyl mercaptan partial pressure in the reaction vessel over the reaction medium ranges from 10 kPA to 180 kPA, at the reaction temperature, and wherein the enzyme used for the enzymatic converting is cystathionine-γ-synthase or O-acetyl homoserine sulfhydrylase or O-succinyl homoserine sulfhydrylase.