| 摘要 |
Heterocyclic compounds of the following formula: <CHEM> wherein the dotted line designates an optional bond, and "het", R<1>, R<2>, R<3>, R<4> and R<5> are as defined in Claim 1, as well as individual stereo isomers and pharmaceutically acceptable acid addition salts thereof are new and described as having potent acetylcholine (AcCh) agonist activity, indicating utility in the treatment of diseases caused by reduced function of AcCh in the brain. Pharmaceutical compositions containing a compound of Formula I, and methods for the preparation of the said novel compounds are likewise described. |
