ALERT SYSTEM FOR HYPO AND HYPERGLYCEMIA PREVENTION BASED ON CLINICAL RISK

摘要

A device for generating alerts for Hypo and Hyperglycemia Prevention from Continuous Glucose Monitoring (CGM) determines a dynamic risk based on both information of glucose level and a trend obtainable from a CGM signals. The device includes a display whose color depends on the DR (for example, red for high DR, green for low risk). When DR exceeds a certain threshold, alerts are generated to suggest the patient to pay attention to the current glucose reading and to its trend, both of which are shown on the display in numbers and symbols (e.g. an arrow with different slope or color).

主权项

1. A system for alerting a patient of hypoglycemia and hyperglycemia risk, comprising:
(a) a continuous glucose monitoring (CGM) device configured to determine periodically a glucose level in the patient, thereby generating a series of glucose levels; (b) a dynamic risk estimation module that is configured to:
(i) evaluate a differential change in glucose level over time (dg/dt) based on the series of glucose levels;(ii) generate a smoothed glucose level that is indicative of the series of glucose levels; and(iii) estimate a dynamic risk based on the smoothed CGM and dg/dt; (c) a comparison circuit that compares the dynamic risk to a predetermined threshold; and (d) a device monitor that is configured to generate a display representative of the smoothed CGM and that is also configured to generate a perceptible alarm when the dynamic risk is greater than the predetermined threshold.