发明名称 |
Processes for the synthesis of oligomeric compounds |
摘要 |
Methods for the preparation of oligonucleotides having bioreversible phosphate blocking groups are disclosed. The oligonucleotides are prepared utilizing amidite type chemistry wherein the bioreversible phosphorus protecting group is formed as an integral part of the amidite reagent. |
申请公布号 |
AU3662799(A) |
申请公布日期 |
1999.11.16 |
申请号 |
AU19990036627 |
申请日期 |
1999.04.23 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
MUTHIAH MANOHARAN;ANDREI GUSAEV |
分类号 |
C07H21/00 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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