发明名称 Methods of treating TTP with immunoglobulin single variable domains and uses thereof.
摘要 The present invention is based on the finding that administration of polypeptides comprising at least one Immunoglobulin single variable domains against vWF to human TTP patients provides a significant decrease in the time to response. The invention provides a polypeptide comprising at least one immunoglobulin single variable domain (ISVD) against von Willebrand Factor (vWF) for use in treating a vWF -related disease in a human in need thereof. The invention further relates to dosage unit forms, kits and medical uses for treating TTP.
申请公布号 NL2013007(B1) 申请公布日期 2016.07.05
申请号 NL20142013007 申请日期 2014.06.16
申请人 ABLYNX N.V. 发明人 CHRISTIAN DUBY
分类号 A61K38/36;A61P7/00 主分类号 A61K38/36
代理机构 代理人
主权项
地址