| 发明名称 |
Inhibitors of tumor necrosis factor alpha |
| 摘要 |
Novel nitriles are inhibitors of tumor necrosis factor alpha and phosphodiesterase and can be used to combat cachexia, endotoxic shock, retrovirus replication, asthma, and inflammatory conditions. A typical embodiment is 3-Phthalimido-3-(3,4-dimcthoxyphenyl)propionitrile. |
| 申请公布号 |
AU6963296(A) |
申请公布日期 |
1997.03.19 |
| 申请号 |
AU19960069632 |
申请日期 |
1996.08.29 |
| 申请人 |
CELGENE CORPORATION;GEORGE W. MULLER;MARY SHIRE |
发明人 |
GEORGE W. MULLER;MARY SHIRE |
| 分类号 |
A61K31/40;A61K31/00;A61K31/403;A61K31/4035;A61P1/00;A61P1/04;A61P29/00;A61P31/00;A61P31/12;A61P35/00;A61P35/02;A61P43/00;C07D209/46;C07D209/48 |
主分类号 |
A61K31/40 |
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