发明名称 |
Liposomal vaccine |
摘要 |
The invention provides liposomal vehicles for encapsulating relatively high levels of immunogenic protein substances including immunogens directed against hormones and hormone receptors, such as gastrin and gonadotropin releasing hormone and their receptors. The liposome encapsulating large amounts of immunogens can be injected parenterally to induce effective immune responses without exhibiting significant adverse tissue reactogenicity. Methods for production of the liposomal vaccines and methods of their administration for treatment of diseases and conditions associated with the cognate hormones are also provided.
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申请公布号 |
US2005169979(A1) |
申请公布日期 |
2005.08.04 |
申请号 |
US20050036690 |
申请日期 |
2005.01.14 |
申请人 |
MICHAELI DOV;GRIMES STEPHEN;BARENHOLZ YECHEZKEL;EVEN-CHEN SIMCHA;HAGAN SUSAN A. |
发明人 |
MICHAELI DOV;GRIMES STEPHEN;BARENHOLZ YECHEZKEL;EVEN-CHEN SIMCHA;HAGAN SUSAN A. |
分类号 |
A61K9/127;A61K39/00;C12N5/02;C12N15/88;(IPC1-7):A61K39/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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