METHOD FOR TREATMENT OF PROLIFERATIVE DISEASE UTILIZING INHIBITION OF FORMATION OF SYNOVIOLIN HOMOOLIGOMER

摘要

Disclosed is a therapeutic agent for at least one disease selected from the group consisting of a proliferative disease, a neurogenic disease and an allergic disease which can inhibit the self-ubiquitination of synoviolin. Also disclosed is a method for screening a therapeutic agent for at least one disease selected from the group consisting of a proliferative disease, a neurogenic disease and an allergic disease, the method comprising contacting a candidate substance with synoviolin, determining whether or not the candidate substance inhibits the self-ubiquitination of synoviolin, and selecting the candidate substance as the therapeutic agent when the candidate substance inhibits the self-ubiquitination of synoviolin.