IMMUNOHISTOCHEMICAL STAINING COMPOSITION

摘要

An immunohistochemical staining composition characterized by containing a diagnostic marker containing an antibody having a fluorescent functional group and a substance selected from the group consisting of glycerophospholipids, fatty acids and sugar derivatives serving as a surfactant. The composition is excellent in fluorescence intensity and is free from the fear of damages to biological tissues or DNAs caused by ultraviolet excitation, thus being useful for biological immunohistochemical staining. The composition makes it possible to efficiently and safely conduct, for example, the quasi-intracorporeal early diagnosis of malignant neoplasm of the epithelial tissues, such as esophageal carcinoma, gastric cancer or colon cancer, with an infrared endoscope and the specification and diagnosis of foci in a surgical operation.