PYRAZOLOPYRIMIDINE ANALOGS AND THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS

摘要

The present invention relates to Pyrazolopyrimidine Analogs, methods of m aking Pyrazolopyrimidine Analogs, compositions comprising a Pyrazolopyrimidi ne Analog, and methods for treating mTOR -related disorders comprising admin istering to a subject in need thereof an effective amount of a Pyrazolopyrim idine Analog. The invention also relates to treating PI3K -related disorders comprising administering to a subject in need thereof an effective amount o f a Pyrazolopyrimidine Analog.