| 发明名称 | Amelioration of intestinal fibrosis and treatment of Crohn's disease | ||
| 摘要 | Methods of treating patients with inflammatory bowel disease, intestinal fibrosis, or Crohn's disease involve administering a therapeutic amount of CARD-024 or related compound. | ||
| 申请公布号 | US9517241(B2) | 申请公布日期 | 2016.12.13 |
| 申请号 | US201615051850 | 申请日期 | 2016.02.24 |
| 申请人 | The Regents Of The University Of Michigan | 发明人 | Simpson Robert U.;Higgins Peter D. R.;Johnson Laura A. |
| 分类号 | A61K31/59;C07C401/00;A61K9/00;A61K31/592;A61K45/06 | 主分类号 | A61K31/59 |
| 代理机构 | Harness, Dickey & Pierce, PLC | 代理人 | Harness, Dickey & Pierce, PLC |
| 主权项 | 1. A method of ameliorating intestinal fibrosis in a subject, the method comprising administering to the subject a composition comprising a compound of Formula (I) wherein Et is ethyl, wherein the dashed line indicates a single bond or a double bond in the E configuration between carbon 22 and carbon 23, and wherein the configuration at carbon 24 to which Et is attached is in the R configuration or the S configuration. | ||
| 地址 | Ann Arbor MI US | ||