| 摘要 |
6-Dimethylaminomethyl-1-phenyl cyclohexane derivs. of formula (I) are new: R<1> = H, OH, Cl or F; R<2>, R<3> = H, 1-4C alkyl, benzyl, CF3, OH, OCH2Ph, 1-4C alkoxy, Cl or F; R<4> = H, Me, PO(1-4C alkoxy)2, CO(1-5C alkoxy), CO-NH-C6H4-(1-3C alkyl), CO-C6H4-R<5>, CO-(1-5C alkyl), CO-CHR<6>-NHR<7> or opt. substd. pyridyl, thienyl, thiazolyl or phenyl; R<5> = OC(O)-(1-3C alkyl) in ortho position, or CH2-N(R<8>)2 in meta- or para-position; R<8> = 1-4C alkyl; or NR<8>R<8> = 4-morpholino; R<6>, R<7> = H or 1-6C alkyl; provided that: (i) one of R<2>, R<3> = H; (ii) when R<2> and R<3> = H, then R<4> is not Me if R<1> = H, OH or Cl; and (iii) R<4> is not H when R<1> = OH. |
