| 发明名称 |
BAFF mutants with at least one amino acid substitution and methods of their production |
| 摘要 |
The invention relates to novel proteins with BAFF dominant negative antagonist, receptor antagonist activity and agonist activity and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of BAFF or APRIL-related disorders. |
| 申请公布号 |
AU2004220078(A1) |
申请公布日期 |
2004.09.23 |
| 申请号 |
AU20040220078 |
申请日期 |
2004.03.05 |
| 申请人 |
XENCOR, INC. |
发明人 |
JOHN R. DESJARLAIS;EUGENE ZHUKOVSKY;ADAM READ THOMASON |
| 分类号 |
C07K14/705;A61K38/00;C07K14/525;C12N15/63 |
主分类号 |
C07K14/705 |
| 代理机构 |
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代理人 |
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| 主权项 |
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