发明名称 |
PHOSPHOLIPID DERIVATIVE |
摘要 |
<p>A phospholipid derivative, utilizable for modification of liposomes and the like, which is a copolymer containing, as essential component units, a component unit A represented by the formula (1), a component unit B represented by the formula (2A) and/or the formula (2B), and a component unit C represented by the formula (3) ÄR<1> and R<2> represent hydrogen atom or methyl group, provided that R<1> and R<2> do not simultaneously represent methyl group; R<3> represents a divalent hydrocarbon group having 1 to 3 carbon atoms; AO represents an oxyalkylene group having 2 to 4 carbon atoms; m represents an average molar number of the added oxyalkylene groups and is a number in the range represented as 4 </= m </= 100; R<4> represents hydrogen atom, a hydrocarbon group or acyl group having 1 to 20 carbon atoms; R<5>CO and R<6>CO represent an acyl group having 8 to 24 carbon atoms; R<7> represents a divalent hydrocarbon group having 2 to 4 carbon atoms; and X and Y represent hydrogen atom, an alkali metal atom, ammonium or an organic ammoniumÜ wherein a molar ratio of the component unit A relative to a total of the component unit B and the component unit C is from 7/3 to 3/7, and the component unit C is contained at a ratio of from 1 to 4 moles per 1 mole of the copolymer. <CHEM></p> |
申请公布号 |
EP1550675(A1) |
申请公布日期 |
2005.07.06 |
申请号 |
EP20030798560 |
申请日期 |
2003.09.30 |
申请人 |
NOF CORPORATION;DAIICHI PHARMACEUTICAL CO., LTD. |
发明人 |
OHHASHI, SYUNSUKE;KUBO, KAZUHIRO;ITOH, CHIKA;YASUKOHCHI, TOHRU;KIKUCHI, H.;SUZUKI, N.;TAKAHASHI, M.;YAMAUCHI, H. |
分类号 |
A61K8/81;C08F8/40;G01R5/16;A61K8/14;A61K9/127;A61K31/795;A61K45/00;A61K47/32;A61P35/00;A61Q19/00;C08L53/00;(IPC1-7):C08F8/40;A61K7/00 |
主分类号 |
A61K8/81 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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