TREATMENT OF ISCHEMIC EYE DISEASE BY THE SYSTEMATIC PHARMACEUTICAL ACTIVATION OF HYPOXIA INDUCIBLE FACTOR (HIF)
摘要
The present invention consists of a method of treating a subject with an ischemic eye disease associated with the down-regulation of HIF comprising administering to the subject an effective amount of a compound that induces HIF activity and/or induces EPO activity to induce and maintain growth or normal retinal blood vessels in the early stage of the disease.
申请公布号
WO2009035534(A2)
申请公布日期
2009.03.19
申请号
WO2008US10413
申请日期
2008.09.05
申请人
THE CLEVELAND CLINIC FOUNDATION;SEARS, JONATHAN, E.;HOPPE, GEORGE, B.;EBRAHEM, QUTEBA