发明名称 |
Pyrimidinyl-diazospiro compounds |
摘要 |
The invention relates to spiro derivatives, to the use of said derivatives intreating diseases and conditions mediated by modulation of voltage-gated sodium channels, to compositions containing said derivatives and processes for their preparation. |
申请公布号 |
US9376445(B2) |
申请公布日期 |
2016.06.28 |
申请号 |
US201314403473 |
申请日期 |
2013.05.22 |
申请人 |
Convergence Pharmaceuticals Limited |
发明人 |
Giblin Gerard M. P.;MacPherson David T.;Witty David R.;Stanway Steven J. |
分类号 |
C07D471/10;C07D487/10;A61K31/407;A61K31/438 |
主分类号 |
C07D471/10 |
代理机构 |
Honigman Miller Schwartz and Cohn LLP |
代理人 |
Honigman Miller Schwartz and Cohn LLP ;Doyle Kathryn D.;O'Brien Jonathan P. |
主权项 |
1. A compound of formula (I) which is 7-methyl-2-[4-methyl-6-[4-(trifluoromethyl)-phenyl]pyrimidin-2-yl]-1,7-diazaspiro[4.4]nonan-6-one: or a pharmaceutically acceptable salt or solvate thereof. |
地址 |
London GB |