ANTI-CANCER AGENT AND ANTIMETASTATIC AGENT USING FSTL1, AND CONCOMITANT DRUG FOR SAME

摘要

The present invention provides an anti-FSTL1 antibody, or a fragment or functional equivalent thereof, said antibody having an- epitope in a site selected from a group consisting of positions 48-100, 148-162, 193-216, 205-228 or 272-289 of the amino acid of SEQ ID NO:1 (human FSTL1 amino acid sequence). Also provided is an agent obtained by combining an FSTL1 suppressor and another anti-cancer agent. The present invention is understood to effectively eliminate immunosuppression, immunodeficiency and other forms of immune breakdown.