| 发明名称 |
DESIGNED ANKYRIN REPEAT PROTEINS BINDING TO HEPATOCYTE GROWTH FACTOR |
| 摘要 |
New designed ankyrin repeat proteins with binding specificity for HGF are described, as well as nucleic acids encoding such HGF binding proteins, pharmaceutical compositions comprising such proteins and the use of such proteins in the treatment of diseases. |
| 申请公布号 |
US2016251404(A1) |
申请公布日期 |
2016.09.01 |
| 申请号 |
US201414891792 |
申请日期 |
2014.06.02 |
| 申请人 |
MOLECULAR PARTNERS AG |
发明人 |
TRESCH Gaby;BAKKER Talitha;PHILLIPS Douglas;MERZ Frieder W.;BINZ Kaspar H. |
| 分类号 |
C07K14/47 |
主分类号 |
C07K14/47 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A recombinant binding protein comprising at least one ankyrin repeat domain, wherein said ankyrin repeat domain binds HGF in PBS with a dissociation constant (KD) below 10−7M. |
| 地址 |
Zürich-Schlieren CH |
